GRIA2 anticorps

N° du produit ABIN361453

Cet anticorps Lapin Polyclonal détecte spécifiquement GRIA2 dans WB. Il présente une réactivité envers Rat.

Aperçu rapide pour GRIA2 anticorps (ABIN361453)

Antigène: GRIA2 (Glutamate Receptor, Ionotropic, AMPA 2 (GRIA2))

Reactivité: Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GRIA2 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-GRIA2 anticorps

Specificité: Specific for the ~100k GluR2 protein.

Réactivité croisée: Rat (Rattus)

Homologie: chicken, human, mouse, non-human primate, Zebrafish

Purification: Antigen Affinity Purified from Pooled Serum

Immunogène: Synthetic peptide corresponding to amino acid residues specific to GluR2 conjugated to KLH

Information d'application

Indications d'application: Recommended Dilution: WB: 1:1000 Quality Control: Western blots performed on each lot.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: 100 μL in 10 mM HEPES (  pH 7.5), 150 mM NaCl, 100 μg per ml BSA and 50 % glycerol.

Stock: -20 °C

Détails sur GRIA2

Antigène: GRIA2 (Glutamate Receptor, Ionotropic, AMPA 2 (GRIA2))

Autre désignation: GRIA2

Sujet: The ion channels activated by glutamate are typically divided into two classes. Those that are sensitive to N-methyl-D-aspartate (NMDA) are designated NMDA receptors (NMDAR) while those activated by (-amino-3-hydroxy-5-methyl-4-isoxalone propionic acid (AMPA) are known as AMPA receptors (AMPAR). The AMPAR are comprised of four distinct glutamate receptor subunits designated (GluR1-4) and they play key roles in virtually all excitatory neurotransmission in the brain (Keinänen et al., 1990,Hollmann and Heinemann, 1994). The GluR2 subunit is thought to play a key role in forms of synaptic plasticity such as LTD (Chung et al., 2003) Anti-GluR2 Western blot of a rat hippocampal (Hipp) lysate showing the specific immunolabeling of the ~100k GluR2 protein.

Poids moléculaire: '100 kDa

ID gène: 29627

UniProt: P19491

Pathways: Signalisation PI3K-Akt